Tryptophan in Nutrition and Health

• Other Authors: Poeggeler, Burkhard (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Medicine; Pharmacology; tryptophan; kynurenine; kynurenic acid; FICZ; AhR; melanoma; proliferation; cell death; aryl hydrocarbon receptor; chronic kidney disease; developmental origins of health and disease (DOHaD); hypertension; indole; melatonin; serotonin; uremic toxin; virus; immunity; codon; depression; chronic mild stress; oxidative stress; tryptophan catabolites pathway; methylation; expression; escitalopram; 5-hydroxytryptophan; natural sources; microbial production; biosynthetic pathways; physiological effects; animal; human; kynurenine pathway; MEL biosynthesis; Saccharomyces cerevisiae; yeast; tryptophan extraction; LC-MS/MS; soybean; skin; atopic dermatitis; psoriasis; severe acute respiratory syndrome; SARS-CoV-2; COVID-19; malignant melanoma; urine; autofluorescence; transplantation; ischemia-reperfusion; tolerance; rejection; indoleamine-2,3-dioxygenase; L-tryptophan; amino acids; MAC-T cell; proteomics; omics; β-casein; mTOR; systemic inflammation; dysbiosis; gut; microbiota; obesity; mice; tyrosine; cytokines; behavior; inflammation; liver morphology; color; cell culture media; LC-MS; antioxidant; cytotoxicity; biomanufacturing; 5-hydroxytryptamine; secretion; metabolism; nitrofurantoin; antibiotics; human serum albumin; molecular interactions; FTIR; fluorescence; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Tryptophan is a rate-limiting essential amino acid and a unique building block of peptides and proteins. This largest amino acid serves as the precursor for the important endogenous indoleamines serotonin, N-acetylserotonin, and melatonin that act as neurotransmitters, neuromodulators, and neurohorm...