The Fungal Cell Wall Integrity Pathway

• Other Authors: Molina, María (Editor), Martín, Humberto (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Research & information: general; Biology, life sciences; Wsc1; membrane sensor; SMALP; detergent-free extraction; fluorescence correlation spectroscopy; transmission electron microscopy; 3D reconstruction; fission yeast; MAPK; cell integrity pathway; S. japonicus; S. pombe; protein kinase C; Pmk1; dimorphism; hyphae; yeast; cell wall integrity; phosphorylation; azoles; clotrimazole; cytokinesis; actomyosin ring; septum; cell integrity; fungi; cell wall; cell wall proteins; signaling pathways; stress tolerance; mannoprotein; budding yeast; morphology; CalMorph; cell wall integrity (CWI) pathway; PKC; GTPases; MAP kinase; morphogenesis; virulence; pathogenesis; Hrr25; Mec1; Tel1; Pkc1; hydroxyurea; UV irradiation; cell wall integrity (CWI); Mtl1; autophagy; glucose; mitophagy; Saccharomyces cerevisiae; histidine kinase; Paracoccidioides; paracoccidioidomycosis; cell cycle; Slt2; checkpoint; DNA damage; conjugation; ploidy; lysis; Cell Integrity Pathway; stress; CWI pathway; UPR; glucosamine; tunicamycin; N-glycosylation; cell wall integrity pathway; MAPK substrate; kinase assay; fungal cell wall; cysteine-rich domain; PAN domain; aromatic clusters; filamentous fungi; signaling pathway; surface sensor; mitogen-activated protein kinase; plant pathogen; application; fungicide; drug target; culture; productivity; stress response; screening; transcription; essential genes; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Adaptation to external changes is necessary for all cells to survive and thrive in diverse environments. Key to these responses are the MAPK-mediated signaling pathways, intracellular communication routes that sense stimuli at the cell surface, and are ubiquitous in all eukaryotic organisms. In the...