Nutraceutical Approaches to Cardiovascular and Metabolic Diseases: Evidence and Opportunities

• Other Authors: Magni, Paolo (Editor), Baragetti, Andrea (Editor), Poli, Andrea (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Research & information: general; Biology, life sciences; Food & society; Atherosclerotic Cardiovascular Diseases; Gut Microbiota; next generation sequencing; oxysterols; 24-OHC; 25-OHC; 27-OHC; cholesterol metabolism; probiotic; cardiovascular risk; hypercholesterolemia; monacolin K; nutraceutical; very-low calorie ketogenic diet; obesity; insulin resistance; diabetic retinopathy; macular xanthophylls; carotenoids; macular pigment; macular pigment optical density; MPOD; lutein; zeaxanthin; meso-zeaxanthin; diabetes; retinal neurodegeneration; neuroprotection; phytosterols; plant sterols; cholesterol; cardiovascular disease; supplements; functional foods; PREDIMED; Mediterranean diet; lipid profile; polyphenols; menopause; body fat; biomarkers; tartaric acid; nutraceuticals; dyslipidaemia; atherosclerosis; tree nuts; peanuts; fatty acids; prospective studies; randomized clinical trials; type-2 diabetes; cancer; hypertension; cognitive function; mortality; body weight; blood lipids; inflammation; dietary lipids; immune-inflammation; microbiota; Cameroonian spice extracts; SW 872 adipocytes; triglyceride accumulation; glucose uptake; oxidative stress; pro-inflammatory cytokines; Prunus domestica L.; chemical characterization; digestive enzyme inhibition; HMG-CoA reductase inhibition; anti-inflammatory activity; guidelines; nutraceutical product; metabolic disease; type 2 diabetes mellitus; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

A major task for health professionals and health systems is effectively preventing and treating cardiovascular and metabolic diseases. This reprint offers an updated set of experimental and clinical information on the usefulness of nutraceutical products for the management of cardiometabolic diseases, which range from obesity and diabetes mellitus and their complications to hypercholesterolemia. The nutraceutical option may be used according the "beyond diet, before drug" strategy and is particularly relevant in the cardiometabolic field. The chapters of this reprint offer a deep insight into relevant issues in this nutraceutical field, such as experimental research for the preclinical identification of interesting compounds of natural origin, quality of nutraceutical products and their efficacy and safety, regulatory aspects, and the quality of evidence-based medicine.