Model-Informed Precision Dosing

• Other Authors: Pérez-Blanco, Jonás Samuel (Editor), Lanao, José Martínez (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Medicine; Pharmaceutical industries; model-informed precision dosing (MIPD); efficacy PKPD indexes; pharmacokinetics; pharmacodynamics; PKPD modeling and simulation; dosing algorithms; nomograms
• Online Access: DOAB: download the publication; DOAB: description of the publication

Model-informed precision dosing (MIPD) is an advanced quantitative approach focusing on individualized treatment optimization. MIPD integrates mathematical models of drugs and diseases combined with individual patient characteristics (e.g., genotype, anthropometric factors, and organ function). MIPD...