Ossifying fibromyxoid tumor: A rare case report with review of literature and its differential diagnosis
Ossifying fibromyxoid tumor (OFMT) is a rare mesenchymal tumor of uncertain histogenesis with intermediate malignant potential presenting commonly in the fifth to sixth decade in the proximal limb and limb girdle. A 65-year-old male patient presented with a slow-growing gluteal mass. Wide local exci...
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| Main Authors: | , , |
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| Format: | Book |
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Wolters Kluwer Medknow Publications,
2024-07-01T00:00:00Z.
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| Summary: | Ossifying fibromyxoid tumor (OFMT) is a rare mesenchymal tumor of uncertain histogenesis with intermediate malignant potential presenting commonly in the fifth to sixth decade in the proximal limb and limb girdle. A 65-year-old male patient presented with a slow-growing gluteal mass. Wide local excision performed showed a well-defined tumor in the subcutaneous plane with a partially hard outer shell. Microscopy showed a moderately cellular tumor having cords and nests of round to ovoid cells with moderate cytoplasm and bland nuclei embedded in a myxo-hyaline matrix. An incomplete peripheral rim of ossification was seen. Pleomorphism/high cellularity was not seen. Mitosis was <2/50 high-power field. On immunohistochemistry, both S100 and desmin were positive. A diagnosis of typical OFMT was rendered. Even though rare with many morphological mimics, OFMT should be diagnosed with precision as most of these tumors are low-grade tumors that require only wide local excision and close follow-up without any adjuvant therapy. |
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| Item Description: | 0377-4929 0974-5130 10.4103/ijpm.ijpm_298_22 |