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Circ-CSNK1G1 promotes cell proliferation, migration, invasion and glycolysis metabolism during triple-negative breast cancer progression by modulating the miR-28-5p/LDHA pathway

Highlights 1. Circ-CSNK1G1 is upregulated in TNBC. 2. Circ-CSNK1G1 knockdown inhibits the proliferation, migration, invasion and glycolysis energy metabolism of TNBC cells. 3. Circ-CSNK1G1 knockdown inhibits tumor formation in vivo. 4. Circ-CSNK1G1 promotes TNBC development by regulating the miR-28-...

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Main Authors: Xiaochen Zan (Author), Wenfang Li (Author), Geng Wang (Author), Jie Yuan (Author), Yongbiao Ai (Author), Jun Huang (Author), Zhi Li (Author)
Format: Book
Published: BMC, 2022-09-01T00:00:00Z.
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Summary:Highlights 1. Circ-CSNK1G1 is upregulated in TNBC. 2. Circ-CSNK1G1 knockdown inhibits the proliferation, migration, invasion and glycolysis energy metabolism of TNBC cells. 3. Circ-CSNK1G1 knockdown inhibits tumor formation in vivo. 4. Circ-CSNK1G1 promotes TNBC development by regulating the miR-28-5p/LDHA pathway.
Item Description:10.1186/s12958-022-00998-z
1477-7827

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