Fast cycling of intermittent hypoxia in a physiomimetic 3D environment: A novel tool for the study of the parenchymal effects of sleep apnea

• Main Authors: Alicia Jurado (Author), Anna Ulldemolins (Author), Helena Lluís (Author), Xavier Gasull (Author), Núria Gavara (Author), Raimon Sunyer (Author), Jorge Otero (Author), David Gozal (Author), Isaac Almendros (Author), Ramon Farré (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Patients with obstructive sleep apnea (OSA) experience recurrent hypoxemic events with a frequency sometimes exceeding 60 events/h. These episodic events induce downstream transient hypoxia in the parenchymal tissue of all organs, thereby eliciting the pathological consequences of OSA. W...