Colchicine causes prenatal cell toxicity and increases tetraploid risk

• Main Authors: Ding Wang (Author), Yingjun Xie (Author), Minyi Yan (Author), Qianying Pan (Author), Yi Liang (Author), Xiaofang Sun (Author)
• Format: Book
• Published: BMC, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Colchicine is a clinical medicine used for relief from gout and familial Mediterranean fever. Because of its toxic effects, intravenous injection of colchicine has been banned, but it is still widely administered orally. We assayed the toxic effects of colchicine in cultured prim...