Cover Image

Atovaquone for treatment of COVID-19: A prospective randomized, double-blind, placebo-controlled clinical trial

Background: An in silico screen was performed to identify FDA approved drugs that inhibit SARS-CoV-2 main protease (Mpro), followed by in vitro viral replication assays, and in vivo pharmacokinetic studies in mice. These studies identified atovaquone as a promising candidate for inhibiting viral rep...

Full description

Saved in:
Bibliographic Details
Main Authors: Mamta K. Jain (Author), James A. De Lemos (Author), Darren K. McGuire (Author), Colby. Ayers (Author), Jennifer L. Eitson (Author), Claudia L. Sanchez (Author), Dena Kamel (Author), Jessica A. Meisner (Author), Emilia V. Thomas (Author), Anita A. Hegde (Author), Satish Mocherla (Author), Joslyn K. Strebe (Author), Xilong Li (Author), Noelle S. Williams (Author), Chao Xing (Author), Mahmoud S. Ahmed (Author), Ping Wang (Author), Hesham A. Sadek (Author), John W. Schoggins (Author)
Format: Book
Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
Subjects:
article
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items