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Toll-Like Receptor 9 Promotes Cardiac Inflammation and Heart Failure during Polymicrobial Sepsis

Background. Aim was to elucidate the role of toll-like receptor 9 (TLR9) in cardiac inflammation and septic heart failure in a murine model of polymicrobial sepsis. Methods. Sepsis was induced via colon ascendens stent peritonitis (CASP) in C57BL/6 wild-type (WT) and TLR9-deficient (TLR9-D) mice. Ba...

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Main Authors: Ralph Lohner (Author), Markus Schwederski (Author), Carolin Narath (Author), Johanna Klein (Author), Georg D. Duerr (Author), Alexandra Torno (Author), Pascal Knuefermann (Author), Andreas Hoeft (Author), Georg Baumgarten (Author), Rainer Meyer (Author), Olaf Boehm (Author)
Format: Book
Published: Hindawi Limited, 2013-01-01T00:00:00Z.
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