The Use of High-dose Corticosteroids in Seriously Ill Children with Acute Viral Bronchiolitis

Introduction:The aim of the present study is to investigate whether high-dose corticosteroids cause a clinical improvement in seriously ill children with acute viral bronchiolitis.Methods:Hospital records of patients diagnosed with acute viral bronchiolitis and admitted to the pediatric intensive ca...

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Bibliographic Details
Main Author: Çelebi Kocaoğlu (Author)
Format: Book
Published: Galenos Yayinevi, 2020-08-01T00:00:00Z.
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Summary:Introduction:The aim of the present study is to investigate whether high-dose corticosteroids cause a clinical improvement in seriously ill children with acute viral bronchiolitis.Methods:Hospital records of patients diagnosed with acute viral bronchiolitis and admitted to the pediatric intensive care unit or general pediatrics service in a tertiary care hospital were reviewed retrospectively. Patients receiving steroids were divided into two subgroups: high-dose and standard-dose corticosteroid recipients. Patients diagnosed with acute viral bronchiolitis but receiving no corticosteroid treatment constituted the control group.Results:While there was no difference between the pre- and post-drug pulse rates of all three groups, a difference was observed in both pre- and post-drug breathing rates between the high-dose steroid and control groups. However, there was no difference between the average pre- and post-drug breathing rates in the high-dose steroid, standard-dose steroid and control groups. There was no regression relationship between the treatment applied and either the pulse rate or the breathing rate in the entire study group.Conclusion:The results of our study show that even at high doses, corticosteroids provide no obvious improvement in the patient's clinical status and do not shorten the length of hospitalisation.
Item Description:2148-7332
2148-7332
10.4274/cayd.galenos.2019.92485