Neostigmine Attenuates Proinflammatory Cytokine Expression in Preoptic Area but Not Choroid Plexus during Lipopolysaccharide-Induced Systemic Inflammation

• Main Authors: Andrzej P. Herman (Author), Dorota Tomaszewska-Zaremba (Author), Marta Kowalewska (Author), Aleksandra Szczepkowska (Author), Małgorzata Oleszkiewicz (Author), Agata Krawczyńska (Author), Maciej Wójcik (Author), Hanna Antushevich (Author), Janina Skipor (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The study was designed to examine whether the administration of neostigmine (0.5 mg/animal), a peripheral inhibitor of acetylcholinesterase (AChE), during an immune/inflammatory challenge provoked by intravenous injection of bacterial endotoxin-lipopolysaccharide (LPS; 400 ng/kg)-attenuates the synt...