Kinsenoside attenuates osteoarthritis by repolarizing macrophages through inactivating NF-κB/MAPK signaling and protecting chondrocytes

• Main Authors: Feng Zhou (Author), Jingtian Mei (Author), Xiuguo Han (Author), Hanjun Li (Author), Shengbing Yang (Author), Minqi Wang (Author), Linyang Chu (Author), Han Qiao (Author), Tingting Tang (Author)
• Format: Book
• Published: Elsevier, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The objective was to investigate the effect of kinsenoside (Kin) treatments on macrophage polarity and evaluate the resulting protection of chondrocytes to attenuate osteoarthritis (OA) progression. RAW264.7 macrophages were polarized to M1/M2 subtypes then administered with different concentrations...