Targeting OPA1-Mediated Mitochondrial Fusion Contributed to Celastrol's Anti-Tumor Angiogenesis Effect
Celastrol, an active triterpenoid extracted from one of the most famous traditional Chinese medicines (TCMs), <i>Tripterygium wilfordii</i> Hook.f., is a novel anti-cancer drug with significant anti-angiogenesis activity. However, the exact molecular mechanisms underlying its anti-tumor...
Saved in:
Main Authors: | Gaofu Li (Author), Lei Zhou (Author), Huifang Deng (Author), Congshu Huang (Author), Ningning Wang (Author), Lanxin Yue (Author), Pengfei Zhang (Author), Yongqiang Zhou (Author), Wei Zhou (Author), Yue Gao (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2022-12-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Inosine: A broad-spectrum anti-inflammatory against SARS-CoV-2 infection-induced acute lung injury via suppressing TBK1 phosphorylation
by: Ningning Wang, et al.
Published: (2023) -
Altered Mitochondrial Opa1-Related Fusion in Mouse Promotes Endothelial Cell Dysfunction and Atherosclerosis
by: Ahmad Chehaitly, et al.
Published: (2022) -
Repeated Aconitine Treatment Induced the Remodeling of Mitochondrial Function via AMPK-OPA1-ATP5A1 Pathway
by: Li-Zhen Qiu, et al.
Published: (2021) -
Effectively suppressed angiogenesis-mediated retinoblastoma growth using celastrol nanomicelles
by: Zhanrong Li, et al.
Published: (2020) -
Mitochondrial Membrane Dynamics-Functional Positioning of OPA1
by: Hakjoo Lee, et al.
Published: (2018)