Mild Crigler-Najjar Syndrome with Progressive Liver Disease-A Multicenter Retrospective Cohort Study

• Үндсэн зохиолчид: Norman Junge (Зохиогч), Hanna Hentschel (Зохиогч), Dorothee Krebs-Schmitt (Зохиогч), Amelie Stalke (Зохиогч), Eva-Doreen Pfister (Зохиогч), Björn Hartleben (Зохиогч), Martin Claßen (Зохиогч), Alexander Querfurt (Зохиогч), Veronika Münch (Зохиогч), Philip Bufler (Зохиогч), Jun Oh (Зохиогч), Enke Grabhorn (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2023-08-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Crigler-Najjar Syndrome (CNS) with residual activity of UDP-glucuronosyltransferase 1A1 (<i>UGT1A1</i>) and no need for daily phototherapy is called mild Crigler-Najjar Syndrome. Most of these patients need medical treatment for enzyme induction (phenobarbital) to lower blood levels of u...