Strong association between serological status and probability of progression to clinical visceral leishmaniasis in prospective cohort studies in India and Nepal.

• Main Authors: Epco Hasker (Author), Paritosh Malaviya (Author), Kamlesh Gidwani (Author), Albert Picado (Author), Bart Ostyn (Author), Sangeeta Kansal (Author), Rudra Pratap Singh (Author), Om Prakash Singh (Author), Ankita Chourasia (Author), Abhishek Kumar Singh (Author), Ravi Shankar (Author), Mary E Wilson (Author), Basudha Khanal (Author), Suman Rijal (Author), Marleen Boelaert (Author), Shyam Sundar (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Asymptomatic persons infected with the parasites causing visceral leishmaniasis (VL) usually outnumber clinically apparent cases by a ratio of 4-10 to 1. We assessed the risk of progression from infection to disease as a function of DAT and rK39 serological titers.We used available data on four coho...