Oxidative stress mediated by gyrophoric acid from the lichen Umbilicaria hirsuta affected apoptosis and stress/survival pathways in HeLa cells

• Главные авторы: Michal Goga (Автор), Martin Kello (Автор), Maria Vilkova (Автор), Klaudia Petrova (Автор), Martin Backor (Автор), Wolfram Adlassnig (Автор), Ingeborg Lang (Автор)
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• Опубликовано: BMC, 2019-08-01T00:00:00Z.
• Предметы: article
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Abstract Background Lichens produce a huge diversity of bioactive compounds with several biological effects. Gyrophoric acid (GA) is found in high concentrations in the common lichen Umbilicaria hirsuta, however evidence for biological activity was limited to anti-proliferative activity described on...