Characteristics, Associated Diseases, and Management of Gram­negative Toe-web Infection: A French Experience

• Main Authors: Anne Goiset (Author), Brigitte Milpied (Author), Aurélie Marti (Author), Jérome Marie (Author), Vaianu Leroy-Colavolpe (Author), Anne Pham-Ledard (Author), Olivier Chosidow (Author), Marie Beylot-Barry (Author)
• Format: Book
• Published: Medical Journals Sweden, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 0001-5555; 1651-2057; 10.2340/00015555-3315
• Keywords: gram-negative toe-web infection; pseudomonas aeruginosa; eczema; contact dermatitis; Dermatology; RL1-803
• Source: Acta Dermato-Venereologica, Vol 99, Iss 12, Pp 1121-1126 (2019)

Gram-negative toe-web infection can cause pain and disability, be complicated by a long healing time, management failure, and cellulitis, and recur due to persistent predisposing factors. To describe the clinical features and management of Gram-negative toe-web infection and evaluate predisposing factors and associated diseases, their management, and the effect of controlling them on the rate of recurrence, we conducted a retrospective real-life study of patients with Gram-negative toe-web infection. Among the 62 patients (sex ratio 9:1), 31 experienced more than one episode of Gram-negative toe-web infection. Pseudomonas aeruginosa was the most prominent bacteria. Predisposing factors/associated diseases were eczema (66%), suspected Tinea pedis (58%), humidity (42%), hyperhidrosis (16%), psoriasis (11%), and vascular disorders (40%). Patients in whom associated diseases, such as eczema or psoriasis, were controlled did not relapse, suggesting the benefit of management of such conditions. We suggest that management of Gram-negative toe-web infection be standardised, with a focus on diagnosis and treatment of associated diseases.