A critical analysis about the supposed role of azithromycin in the treatment of covid-19
After over one year, the coronavirus disease 2019 (covid-19) has still affected millions of people. For this reason, global efforts to promote better treatment of covid-19 have been undertaken focused on the repurposing of existing medications.In Brazil, azithromycin, a broad-spectrum antibiotic, ha...
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| Format: | Book |
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Hospital de Clínicas de Itajubá,
2021-12-01T00:00:00Z.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_02a2bcfe802b4733a0cbcf17a2791aa0 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Ricardo Ruan Santana |e author |
| 700 | 1 | 0 | |a Bárbara Oliva Barbosa |e author |
| 700 | 1 | 0 | |a José Rivaldo de Oliveira Soares |e author |
| 700 | 1 | 0 | |a Rayssa Mielo Colombo |e author |
| 700 | 1 | 0 | |a Victória Rafaela Santos |e author |
| 700 | 1 | 0 | |a Ricardo Guimarães Amaral |e author |
| 700 | 1 | 0 | |a Luciana Nalone Andrade |e author |
| 245 | 0 | 0 | |a A critical analysis about the supposed role of azithromycin in the treatment of covid-19 |
| 260 | |b Hospital de Clínicas de Itajubá, |c 2021-12-01T00:00:00Z. | ||
| 500 | |a 10.21876/rcshci.v11i4.1184 | ||
| 500 | |a 2236-3785 | ||
| 520 | |a After over one year, the coronavirus disease 2019 (covid-19) has still affected millions of people. For this reason, global efforts to promote better treatment of covid-19 have been undertaken focused on the repurposing of existing medications.In Brazil, azithromycin, a broad-spectrum antibiotic, has been used in association with other drugs as an immunomodulatory, anti-inflammatory, and anti-viral agent, regardless of bacterial co-infection. Indeed, data from experimental studies have demonstrated the capacity of this drug in reducing the production of infection-induced pro-inflammatory cytokines, such as IL-8, IL-6, and TNF-alpha. However, observational studies revealed conflicting results regarding its effect, whereas well-conducted clinical trials have not shown a considerable effect of this agent on the improvement of clinical outcomes. This narrative review addressed the possible role of this antibiotic in the management of covid-19, based on data from clinical and preclinical studies. | ||
| 546 | |a EN | ||
| 546 | |a PT | ||
| 690 | |a anti-infective agents | ||
| 690 | |a azithromycin | ||
| 690 | |a covid-19 | ||
| 690 | |a SARS-CoV-2 | ||
| 690 | |a Nursing | ||
| 690 | |a RT1-120 | ||
| 690 | |a Medicine (General) | ||
| 690 | |a R5-920 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Revista Ciências em Saúde, Vol 11, Iss 4 (2021) | |
| 787 | 0 | |n http://186.225.220.186:7474/ojs/index.php/rcsfmit_zero/article/view/1184 | |
| 787 | 0 | |n https://doaj.org/toc/2236-3785 | |
| 856 | 4 | 1 | |u https://doaj.org/article/02a2bcfe802b4733a0cbcf17a2791aa0 |z Connect to this object online. |