Normalization of Overexpressed α-Synuclein Causing Parkinson's Disease By a Moderate Gene Silencing With RNA Interference
The α-synuclein (SNCA) gene is a responsible gene for Parkinson's disease (PD); and not only nucleotide variations but also overexpression of SNCA appears to be involved in the pathogenesis of PD. A specific inhibition against mutant SNCA genes carrying nucleotide variations may be feasible by...
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Main Authors: | Masaki Takahashi (Author), Mari Suzuki (Author), Masashi Fukuoka (Author), Nobuhiro Fujikake (Author), Shoko Watanabe (Author), Miho Murata (Author), Keiji Wada (Author), Yoshitaka Nagai (Author), Hirohiko Hohjoh (Author) |
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Format: | Book |
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Elsevier,
2015-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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