Gestational Exposure to a Viral Mimetic Poly(I:C) Results in Long-Lasting Changes in Mitochondrial Function by Leucocytes in the Adult Offspring

• Główni autorzy: Cecilia Giulivi (Autor), Eleonora Napoli (Autor), Jared Schwartzer (Autor), Milo Careaga (Autor), Paul Ashwood (Autor)
• Format: Książka
• Wydane: Hindawi Limited, 2013-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Maternal immune activation (MIA) is a potential risk factor for autism spectrum disorder (ASD) and schizophrenia (SZ). In rodents, MIA results in changes in cytokine profiles and abnormal behaviors in the offspring that model these neuropsychiatric conditions. Given the central role that mitochondri...