Efficacy of vitamin C and ethanolic extract of Sesamum indicum in promoting fertility in male Wistar rats
Aims: This study investigates the efficacy of ethanolic extract of Sesamum indicum (EES), vitamin C (VC), and EES + VC in promoting fertility and finding a possible link between their profertility effects and their antioxidant activities. Materials and Methods: Forty adult male Wistar rats [Body wei...
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Wolters Kluwer Medknow Publications,
2010-01-01T00:00:00Z.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | doaj_03b13e2e6bc047c8a76b95e836c184e6 | ||
042 | |a dc | ||
100 | 1 | 0 | |a E A Ashamu |e author |
700 | 1 | 0 | |a E O Salawu |e author |
700 | 1 | 0 | |a O O Oyewo |e author |
700 | 1 | 0 | |a A W Alhassan |e author |
700 | 1 | 0 | |a O A Alamu |e author |
700 | 1 | 0 | |a A A Adegoke |e author |
245 | 0 | 0 | |a Efficacy of vitamin C and ethanolic extract of Sesamum indicum in promoting fertility in male Wistar rats |
260 | |b Wolters Kluwer Medknow Publications, |c 2010-01-01T00:00:00Z. | ||
500 | |a 0974-1208 | ||
500 | |a 1998-4766 | ||
500 | |a 10.4103/0974-1208.63115 | ||
520 | |a Aims: This study investigates the efficacy of ethanolic extract of Sesamum indicum (EES), vitamin C (VC), and EES + VC in promoting fertility and finding a possible link between their profertility effects and their antioxidant activities. Materials and Methods: Forty adult male Wistar rats [Body weight (BW) 186.56 ± 0.465 g] were randomly analyzed into four groups of ten rats each: Control, EES G (EES only), VC G (vitamin C only), and EES + VC G (EES in conjunction with vitamin C). Control was given 5 ml/kg BW/day of normal saline orally; EES G was administered 0.3 g/kg BW/day of EES; VC G was administered 15 mg/kg BW/ day of VC; while EES + VC G was administered both 0.3 g/kg BW/day of EES and 15 mg/kg BW/day of VC. All treatments were for 10 weeks. Statistical Analysis Used: Independent-sample T test was used to analyze the obtained results. Results: The results obtained showed that EES, VC, and more importantly EES + VC are capable of significantly increasing BW gain, seminal parameters, testosterone level, and body antioxidant activities. Conclusions: These findings lead to the conclusion that EES + VC as well as ESS and VC promote fertility due to both their testosterone-increasing effects and their antioxidant effects. | ||
546 | |a EN | ||
690 | |a Antioxidant | ||
690 | |a fertility | ||
690 | |a Sesamum indicum | ||
690 | |a sperm count | ||
690 | |a vitamin C | ||
690 | |a Gynecology and obstetrics | ||
690 | |a RG1-991 | ||
655 | 7 | |a article |2 local | |
786 | 0 | |n Journal of Human Reproductive Sciences, Vol 3, Iss 1, Pp 11-14 (2010) | |
787 | 0 | |n http://www.jhrsonline.org/article.asp?issn=0974-1208;year=2010;volume=3;issue=1;spage=11;epage=14;aulast=Ashamu | |
787 | 0 | |n https://doaj.org/toc/0974-1208 | |
787 | 0 | |n https://doaj.org/toc/1998-4766 | |
856 | 4 | 1 | |u https://doaj.org/article/03b13e2e6bc047c8a76b95e836c184e6 |z Connect to this object online. |