Adult's Nesidioblastosis. Case report

• Main Authors: Liesel Pérez Ruiz (Author), Elodia María Rivas Alpízar (Author), Karen García (Author)
• Format: Book
• Published: Centro Provincial de Información de Ciencias Médicas. Cienfuegos, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 1727-897X
• Keywords: nesidioblastosis; adulto; informes de casos; Medicine (General); R5-920; Public aspects of medicine; RA1-1270
• Source: Medisur, Vol 19, Iss 5, Pp 858-862 (2021)

Adult nesidioblastosis is rare, defined as changes in the endocrine pancreas characterized by abnormal proliferation of pancreatic islet cells, diffusely affecting the gland, and causing persistent hyperinsulinemic hypoglycemia in the absence of an insulinoma. A case of a patient who is admitted to the internal medicine service at the "Dr. Gustavo Aldereguía Lima" Cienfuegos Hospital with a hypoglycemic syndrome for study. A 6-hour oral glucose tolerance test was performed with hypoglycemia (1.9mmol / L) at hour 5. 72-hour fasting test: with hypoglycemia at 2 hours with a paradoxical response to insulin, Glycemia and Insulinemia with the symptom. In the multislice abdominal computerized axial tomography, no lesion in the pancreas was evidenced. A distal pancreatectomy of ± 85% of the gland is performed with splenic preservation. The pathology anatomy confirmed nesidioblastosis. Nesidioblastosis in adults is a very rare entity, but it should be taken into account as a differential diagnosis of insulinomas in the absence of an evident lesion in conventional imaging studies.