Network pharmacology and experimental analysis to reveal the mechanism of Dan-Shen-Yin against endothelial to mesenchymal transition in atherosclerosis

• Main Authors: Mengyun Hong (Author), Yubiao Wu (Author), Haiyi Zhang (Author), Jinchao Gu (Author), Juanjuan Chen (Author), Yancheng Guan (Author), Xiude Qin (Author), Yu Li (Author), Jiahui Cao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Atherosclerosis is a chronic inflammatory disease characterized by the formation of plaque and endothelial dysfunction. Under pro-inflammatory conditions, endothelial cells adopt a mesenchymal phenotype by a process called endothelial-to-mesenchymal transition (EndMT) which plays an important role i...