A highly attenuated Vesiculovax vaccine rapidly protects nonhuman primates against lethal Marburg virus challenge.

• Main Authors: Courtney Woolsey (Author), Robert W Cross (Author), Krystle N Agans (Author), Viktoriya Borisevich (Author), Daniel J Deer (Author), Joan B Geisbert (Author), Cheryl Gerardi (Author), Theresa E Latham (Author), Karla A Fenton (Author), Michael A Egan (Author), John H Eldridge (Author), Thomas W Geisbert (Author), Demetrius Matassov (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Marburg virus (MARV), an Ebola-like virus, remains an eminent threat to public health as demonstrated by its high associated mortality rate (23-90%) and recent emergence in West Africa for the first time. Although a recombinant vesicular stomatitis virus (rVSV)-based v...