Activation of the Nrf2 Pathway Prevents Mitochondrial Dysfunction Induced by Caspase-3 Cleaved Tau: Implications for Alzheimer's Disease
Alzheimer's disease (AD) is characterized by memory and cognitive impairment, accompanied by the accumulation of extracellular deposits of amyloid β-peptide (Aβ) and the presence of neurofibrillary tangles (NFTs) composed of pathological forms of tau protein. Mitochondrial dysfunction and oxida...
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Main Authors: | Francisca Villavicencio-Tejo (Author), Margrethe A. Olesen (Author), Alejandra Aránguiz (Author), Rodrigo A. Quintanilla (Author) |
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Format: | Book |
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MDPI AG,
2022-03-01T00:00:00Z.
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