Synthesis and Bioevaluation of New Stable Derivatives of Chrysin-8-<i>C</i>-Glucoside That Modulate the Antioxidant Keap1/Nrf2/HO-1 Pathway in Human Macrophages

• Main Authors: Javier Ávila-Román (Author), Lirenny Quevedo-Tinoco (Author), Antonio J. Oliveros-Ortiz (Author), Sara García-Gil (Author), Gabriela Rodríguez-García (Author), Virginia Motilva (Author), Mario A. Gómez-Hurtado (Author), Elena Talero (Author)
• Format: Book
• Published: MDPI AG, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<b>Background/Objectives</b>: The beneficial effects of the flavonoid chrysin can be reduced by its poor oral bioavailability. It has been shown that chrysin-8-C-glucoside (<b>1</b>) has a better absorption capability. The aim of this study was to evaluate the antioxidant and...