Novel Phenothiazine/Donepezil-like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer's Disease

• Main Authors: Alessia Carocci (Author), Alexia Barbarossa (Author), Rosalba Leuci (Author), Antonio Carrieri (Author), Leonardo Brunetti (Author), Antonio Laghezza (Author), Marco Catto (Author), Francesco Limongelli (Author), Sílvia Chaves (Author), Paolo Tortorella (Author), Cosimo Damiano Altomare (Author), Maria Amélia Santos (Author), Fulvio Loiodice (Author), Luca Piemontese (Author)
• Format: Bog
• Udgivet: MDPI AG, 2022-08-01T00:00:00Z.
• Fag: article
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Alzheimer's disease (AD) is a complex multi-factorial neurodegenerative disorder for which only few drugs (including donepezil, DPZ) are available as symptomatic treatments; thus, researchers are focusing on the development of innovative multi-target directed ligands (MTDLs), which could also a...