Novel Phenothiazine/Donepezil-like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer's Disease

• Hauptverfasser: Alessia Carocci (Verfasst von), Alexia Barbarossa (Verfasst von), Rosalba Leuci (Verfasst von), Antonio Carrieri (Verfasst von), Leonardo Brunetti (Verfasst von), Antonio Laghezza (Verfasst von), Marco Catto (Verfasst von), Francesco Limongelli (Verfasst von), Sílvia Chaves (Verfasst von), Paolo Tortorella (Verfasst von), Cosimo Damiano Altomare (Verfasst von), Maria Amélia Santos (Verfasst von), Fulvio Loiodice (Verfasst von), Luca Piemontese (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2022-08-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Alzheimer's disease (AD) is a complex multi-factorial neurodegenerative disorder for which only few drugs (including donepezil, DPZ) are available as symptomatic treatments; thus, researchers are focusing on the development of innovative multi-target directed ligands (MTDLs), which could also a...