Novel Phenothiazine/Donepezil-like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer's Disease

• Главные авторы: Alessia Carocci (Автор), Alexia Barbarossa (Автор), Rosalba Leuci (Автор), Antonio Carrieri (Автор), Leonardo Brunetti (Автор), Antonio Laghezza (Автор), Marco Catto (Автор), Francesco Limongelli (Автор), Sílvia Chaves (Автор), Paolo Tortorella (Автор), Cosimo Damiano Altomare (Автор), Maria Amélia Santos (Автор), Fulvio Loiodice (Автор), Luca Piemontese (Автор)
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• Опубликовано: MDPI AG, 2022-08-01T00:00:00Z.
• Предметы: article
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Alzheimer's disease (AD) is a complex multi-factorial neurodegenerative disorder for which only few drugs (including donepezil, DPZ) are available as symptomatic treatments; thus, researchers are focusing on the development of innovative multi-target directed ligands (MTDLs), which could also a...