Anti-Inflammatory Effects of Flavonoids: Genistein, Kaempferol, Quercetin, and Daidzein Inhibit STAT-1 and NF-κB Activations, Whereas Flavone, Isorhamnetin, Naringenin, and Pelargonidin Inhibit only NF-κB Activation along with Their Inhibitory Effect on iNOS Expression and NO Production in Activated Macrophages

• Main Authors: Mari Hämäläinen (Author), Riina Nieminen (Author), Pia Vuorela (Author), Marina Heinonen (Author), Eeva Moilanen (Author)
• Format: Book
• Published: Hindawi Limited, 2007-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In inflammation, bacterial products and proinflammatory cytokines induce the formation of large amounts of nitric oxide (NO) by inducible nitric oxide synthase (iNOS), and compounds that inhibit NO production have anti-inflammatory effects. In the present study, we systematically investigated the ef...