High affinity human antibody fragments to dengue virus non-structural protein 3.

• Main Authors: Nicole J Moreland (Author), Moon Y F Tay (Author), Elfin Lim (Author), Prasad N Paradkar (Author), Danny N P Doan (Author), Yin Hoe Yau (Author), Susana Geifman Shochat (Author), Subhash G Vasudevan (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: The enzyme activities catalysed by flavivirus non-structural protein 3 (NS3) are essential for virus replication. They are distributed between the N-terminal protease domain in the first one-third and the C-terminal ATPase/helicase and nucleoside 5' triphosphatase domain which forms...