Use of solid dispersions to increase stability of dithranol in topical formulations

• Main Authors: Marilene Estanqueiro (Author), Jaime Conceição (Author), Maria Helena Amaral (Author), José Manuel Sousa Lobo (Author)
• Format: Bog
• Udgivet: Universidade de São Paulo, 2014-09-01T00:00:00Z.
• Fag: article
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The present study was planned to improve the stability of dithranol using solid dispersions (SD). Two different SD at a 1:9 ratio of dithranol/excipient were prepared: one of them using glyceryl behenate as excipient and the other using a mixture of argan oil with stearic acid (1:8 ratio) as excipie...