Use of solid dispersions to increase stability of dithranol in topical formulations

• Ngā kaituhi matua: Marilene Estanqueiro (Author), Jaime Conceição (Author), Maria Helena Amaral (Author), José Manuel Sousa Lobo (Author)
• Hōputu: Pukapuka
• I whakaputaina: Universidade de São Paulo, 2014-09-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

The present study was planned to improve the stability of dithranol using solid dispersions (SD). Two different SD at a 1:9 ratio of dithranol/excipient were prepared: one of them using glyceryl behenate as excipient and the other using a mixture of argan oil with stearic acid (1:8 ratio) as excipie...