The 5-HT4 Agonists Cisapride, Mosapride, and CJ-033466, a Novel Potent Compound, Exhibit Different Human Ether-a-go-go-Related Gene (hERG)-Blocking Activities
The blocking effect of three 5-HT4 agonists, cisapride, mosapride, and the newly discovered CJ-033466 on the human ether-a-go-go-related gene (hERG) channel was studied using a whole cell patch-clamp technique in HEK293 cells. Cisapride was found to be the most potent of the hERG blockers. CJ-033466...
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| Main Authors: | , , |
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| Formato: | Libro |
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Elsevier,
2007-01-01T00:00:00Z.
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| Acceso en liña: | Connect to this object online. |
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| Número de Clasificación: |
A1234.567 |
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| Copia 1 | Dispoñible |