Inhibition of RAGE Attenuates Cigarette Smoke-Induced Lung Epithelial Cell Damage via RAGE-Mediated Nrf2/DAMP Signaling

• Autors principals: Hanbyeol Lee (Autor), Jooyeon Lee (Autor), Seok-Ho Hong (Autor), Irfan Rahman (Autor), Se-Ran Yang (Autor)
• Format: Llibre
• Publicat: Frontiers Media S.A., 2018-07-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

The oxidative stress and cellular apoptosis by environmental factor including cigarette smoke induces alveolar airway remodeling leading to chronic obstructive pulmonary disease (COPD). Recently, the receptor for advanced glycan end products (RAGE) which is highly expressed in alveolar epithelium is...