Human IgG1 Responses to Surface Localised Schistosoma mansoni Ly6 Family Members Drop following Praziquantel Treatment.

• Main Authors: Iain W Chalmers (Author), Colin M Fitzsimmons (Author), Martha Brown (Author), Christine Pierrot (Author), Frances M Jones (Author), Jakub M Wawrzyniak (Author), Narcis Fernandez-Fuentes (Author), Edridah M Tukahebwa (Author), David W Dunne (Author), Jamal Khalife (Author), Karl F Hoffmann (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The heptalaminate-covered, syncytial tegument is an important anatomical adaptation that enables schistosome parasites to maintain long-term, intravascular residence in definitive hosts. Investigation of the proteins present in this surface layer and the immune responses elicited by them during infe...