Evaluation of Chitosan Derivative Microparticles Encapsulating Superparamagnetic Iron Oxide and Doxorubicin as a pH-Sensitive Delivery Carrier in Hepatic Carcinoma Treatment: An in vitro Comparison Study

• Автори: Meng-Yi Bai (Автор), Sung-Ling Tang (Автор), Meng-Han Chuang (Автор), Ting-Ying Wang (Автор), Po-da Hong (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2018-09-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

We developed a novel, pH-sensitive drug delivery microparticle based on N-palmitoyl chitosan (NPCS) to transport the superparamagnetic iron oxide (SPIO) and anticancer drug doxorubicin (DOX). The characteristics of NPCS were characterized through nuclear magnetic resonance. Our results based on test...