Identifying Critical Binder Attributes to Facilitate Binder Selection for Efficient Formulation Development in a Continuous Twin Screw Wet Granulation Process

• Main Authors: Lise Vandevivere (Author), Maxine Vangampelaere (Author), Christoph Portier (Author), Cedrine de Backere (Author), Olaf Häusler (Author), Thomas De Beer (Author), Chris Vervaet (Author), Valérie Vanhoorne (Author)
• Format: Book
• Published: MDPI AG, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The suitability of pharmaceutical binders for continuous twin-screw wet granulation was investigated as the pharmaceutical industry is undergoing a switch from batch to continuous manufacturing. Binder selection for twin-screw wet granulation should rely on a scientific approach to enable efficient...