Selective Serotonin Reuptake Inhibitors and Clozapine: Clinically Relevant Interactions and Considerations

• Main Authors: Amber N. Edinoff (Author), Juliana M. Fort (Author), Joshua J. Woo (Author), Christopher D. Causey (Author), Caroline R. Burroughs (Author), Elyse M. Cornett (Author), Adam M. Kaye (Author), Alan D. Kaye (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The monoamine hypothesis of depression attributes the symptoms of major depressive disorders to imbalances of serotonin, noradrenaline, and dopamine in the limbic areas of the brain. The preferential targeting of serotonin receptor (SERT) by selective serotonin reuptake inhibitors (SSRIs) has offere...