The myopathy-causing mutation DNM2-S619L leads to defective tubulation in vitro and in developing zebrafish
DNM2 is a ubiquitously expressed GTPase that regulates multiple subcellular processes. Mutations in DNM2 are a common cause of centronuclear myopathy, a severe disorder characterized by altered skeletal muscle structure and function. The precise mechanisms underlying disease-associated DNM2 mutation...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
The Company of Biologists,
2014-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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