Evaluation of guanidine antifungal solutions for denture base resin: an in vitro study
Background: The purposes of this study were: (1) to formulate polyhexamethylene guanidine hydrochloride (PHMGH) solutions at different concentrations; (2) to evaluate their antifungal activity against a mature biofilm of Candida albicans on acrylic resins; (3) to evaluate possible effects on acrylic...
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Universidade Federal do Rio Grande do Sul. Faculdade de Odontologia,
2020-12-01T00:00:00Z.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | doaj_06b249ea138445d598c95916d6af6e15 | ||
042 | |a dc | ||
100 | 1 | 0 | |a Maria Eduarda Rodrigues Gama |e author |
700 | 1 | 0 | |a Vicente Castelo Branco Leitune |e author |
700 | 1 | 0 | |a Isadora Martini Garcia |e author |
700 | 1 | 0 | |a Stéfani Becker Rodrigues |e author |
700 | 1 | 0 | |a Fabrício Mezzomo Collares |e author |
245 | 0 | 0 | |a Evaluation of guanidine antifungal solutions for denture base resin: an in vitro study |
260 | |b Universidade Federal do Rio Grande do Sul. Faculdade de Odontologia, |c 2020-12-01T00:00:00Z. | ||
500 | |a 0566-1854 | ||
500 | |a 2177-0018 | ||
500 | |a 10.22456/2177-0018.104096 | ||
520 | |a Background: The purposes of this study were: (1) to formulate polyhexamethylene guanidine hydrochloride (PHMGH) solutions at different concentrations; (2) to evaluate their antifungal activity against a mature biofilm of Candida albicans on acrylic resins; (3) to evaluate possible effects on acrylic resins flexural strength and surface roughness. Methods: PHMGH solutions were formulated with distilled water and 0.125, 0.250, or 0.5 wt.% of PHMGH. One group without PHMGH was used as control. For antifungal activity analysis, acrylic resin specimens were contaminated with C. albicans. Specimens were immersed in PHMGH solutions or distilled water for 5 or 10 min. Ultimate flexural strength and surface roughness of acrylic resins were evaluated. Results: All PHMGH solutions at 5 or 10 min showed antifungal activity compared to the control group (p | ||
546 | |a EN | ||
546 | |a PT | ||
690 | |a acrylic resins | ||
690 | |a antifungal agents | ||
690 | |a candidiasis | ||
690 | |a guanidine | ||
690 | |a dentures | ||
690 | |a Dentistry | ||
690 | |a RK1-715 | ||
655 | 7 | |a article |2 local | |
786 | 0 | |n Revista da Faculdade de Odontologia de Porto Alegre, Vol 61, Iss 2, Pp 39-49 (2020) | |
787 | 0 | |n https://seer.ufrgs.br/RevistadaFaculdadeOdontologia/article/view/104096 | |
787 | 0 | |n https://doaj.org/toc/0566-1854 | |
787 | 0 | |n https://doaj.org/toc/2177-0018 | |
856 | 4 | 1 | |u https://doaj.org/article/06b249ea138445d598c95916d6af6e15 |z Connect to this object online. |