Microarrays. The bridges in the knowledge of mental retardarion diagnosed in childhood
Mental retardation (MR), is a common neurological condition in children. Its etiology may be genetic or environmental. In the first case, all the disorders that cause it have not been identified and a considerable number of patients do not have an accurate diagnosis. Microarrays are derived from com...
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| Main Authors: | , , |
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| Format: | Book |
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Instituto Nacional de Pediatría,
2014-07-01T00:00:00Z.
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| Summary: | Mental retardation (MR), is a common neurological condition in children. Its etiology may be genetic or environmental. In the first case, all the disorders that cause it have not been identified and a considerable number of patients do not have an accurate diagnosis. Microarrays are derived from comparative genomic hybridiza- tion (CGH), which can determine sites of deletions, insertions or translocations. This technique has made it possible to determine chromosomal syndromes not previously described such as: 17q21.31 deletion, deletion 15q24 or 1q21 deletion. It can be done in large populations or be individualized. The intro- duction of this technique has begun to resolve doubts regarding monogenic or polygenic RMI. |
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| Item Description: | 0186-2391 2395-8235 10.18233/APM34No5pp275-279 |