Single-run reversed-phase HPLC method for determining sertraline content, enantiomeric purity, and related substances in drug substance and finished product

• Prif Awduron: Alessia Rosetti (Awdur), Rosella Ferretti (Awdur), Leo Zanitti (Awdur), Adriano Casulli (Awdur), Claudio Villani (Awdur), Roberto Cirilli (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Elsevier, 2020-12-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

A direct enantio-, diastereo-, and chemo-selective high-performance liquid chromatographic method was developed for determining the content, enantiomeric purity, and related substances of the chiral antidepressant drug sertraline HCl in a single chromatographic run. The separation was achieved on a...