Functional and clinical relevance of novel and known PCSK1 variants for childhood obesity and glucose metabolism
Objective: Variants in Proprotein Convertase Subtilisin/Kexin Type 1 (PCSK1) may be causative for obesity as suggested by monogenic cases and association studies. Here we assessed the functional relevance in experimental studies and the clinical relevance through detailed metabolic phenotyping of ne...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2017-03-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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