Should we "eliminate" PDA shunt in preterm infants? A narrative review

The patent ductus arteriosus frequently poses a significant morbidity in preterm infants, subjecting their immature pulmonary vascular bed to substantial volume overload. This, in turn, results in concurrent hypoperfusion to post-ductal organs, and subsequently alters cerebral blood flow. In additio...

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Bibliographic Details
Main Authors: Aimann Surak (Author), Amneet Sidhu (Author), Joseph Y. Ting (Author)
Format: Book
Published: Frontiers Media S.A., 2024-02-01T00:00:00Z.
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Summary:The patent ductus arteriosus frequently poses a significant morbidity in preterm infants, subjecting their immature pulmonary vascular bed to substantial volume overload. This, in turn, results in concurrent hypoperfusion to post-ductal organs, and subsequently alters cerebral blood flow. In addition, treatment has not demonstrated definitive improvements in patient outcomes. Currently, the optimal approach remains a subject of considerable debate with ongoing research controversy regarding the best approach. This article provides a comprehensive review of existing literature.
Item Description:2296-2360
10.3389/fped.2024.1257694