Cover Image

Synthesis, characterization and pharmacological evaluation of different 1,3,4-oxadiazole and acetamide derivatives of ethyl nipecotate

A new series of N-substituted derivatives of 2-[(5-{1-[(4-chlorophenyl)sulfonyl]-3-piperidinyl}-1,3,4-oxadiazol-2-yl)sulfanyl]acetamide (6a-w) has been designed and synthesized with multifunctional moieties. The synthesized compounds were evaluated for their antibacterial and anti-enzymatic potentia...

Full description

Saved in:

Bibliographic Details
Main Authors:	Khadija Nafeesa (Author), Aziz- (Author), Muhammad A. Abbasi (Author), Sabahat Z. Siddiqui (Author), Shahid Rasool (Author), Syed A.A. Shah (Author)
Format:	Book
Published:	Faculty of Pharmacy, Cairo University, 2017-12-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Synthesis, spectral analysis and pharmacological study of N'- substituted-2-(5-((2,4-dimethylphenoxy)methyl)-1,3,4-oxadiazol-2-ylthio)acetohydrazides
by: Shahid Rasool, et al.

Convergent synthesis of new N -substituted 2-{[5-(1H -indol-3-ylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetamides as suitable therapeutic agents
by: Kaniz Rubab, et al.
Published: (2015)

Synthesis of some new 5-substituted-2-((6-chloro-3,4-methylenedioxyphenyl)methylthio)-1,3,4-oxadiazole derivatives as suitable antibacterial inhibitors
by: Aziz-, et al.
Published: (2015)

Synthesis of some novel enzyme inhibitors and antibacterial agents derived from 5-(1-(4-tosyl)piperidin-4-yl)-1,3,4-oxadiazol-2-thiol
by: Almas Sattar, et al.

Synthesis of 1,3,4-Oxadiazole Derivatives from Ethyl-2-Piperidone-3-Carboxylate
by: M. A. Sheat, et al.
Published: (2012)

Synthesis and antitumor activity of 1,3,4-oxadiazole substituted 2-(5-ylidene-2,4-dioxothiazolidin-3-yl)-acetamides
by: Maryan Lelyukh, et al.
Published: (2023)

Synthesis of Some New Substituted 1,3,4-Oxadiazole and 1,3,4-Thiadiazole Derivatives
by: Amena A. Ahmed
Published: (2018)

Synthesis of Some Substituted 1,3,4-Oxadiazoles from Hydrazones
by: Khalid Daoud, et al.
Published: (2009)

Biological activity of synthesized 5-{1-[(4-chlorophenyl)sulfonyl]piperidin-4-yl}-2-mercapto-1,3,4-oxadiazole derivatives demonstrated by in silico and BSA binding studies
by: Javed Iqbal, et al.
Published: (2020)

Research progress on the synthesis and pharmacology of 1,3,4-oxadiazole and 1,2,4-oxadiazole derivatives: a mini review
by: Jing-Jing Wang, et al.
Published: (2022)

Synthesis and Anticancer Evaluation of New 1,3,4-Oxadiazole Derivatives
by: Camelia Elena Stecoza, et al.
Published: (2021)

Synthesis, in silico analysis and antidepressant activity of 1,3,4-oxadiazole derivatives
by: Banylla Felicity Dkhar Gatphoh, et al.
Published: (2022)

Synthesis and Characterization of New 1,3,4-Oxadiazole Derivatives from Sulfathiazole
by: Jassim Jassim, et al.
Published: (2024)

Naproxen Based 1,3,4-Oxadiazole Derivatives as EGFR Inhibitors: Design, Synthesis, Anticancer, and Computational Studies
by: Mohammad Mahboob Alam, et al.
Published: (2021)

Synthesis of 2-Isobutyl, 2-Isobutyl-5-aryl and 2-Isobutyl-5-thiol-1,3,4-Oxadiazoles
by: Hadil S. Aziz, et al.
Published: (2007)

Synthesis of some substituted 1,3,4-oxadiazoles, thiadiazoles and 1,2,4-triazoles
by: Shereen R. Mohamed
Published: (2009)

Synthesis and antimicrobial evaluation of some 2,5 disubstituted 1,3,4-oxadiazole derivatives
by: Elham Jafari, et al.
Published: (2017)

Synthesis of new 2-{2,3-dihydro-1,4-benzodioxin-6-yl[(4-methylphenyl) sulfonyl]amino}-N-(un/substituted-phenyl)acetamides as α-glucosidase and acetylcholinesterase inhibitors and their in silico study
by: Muhammad Athar Abbasi, et al.

Design, synthesis and in vitro antiproliferative activity of new thiazolidinedione-1,3,4-oxadiazole hybrids as thymidylate synthase inhibitors
by: Zohor Mohammad Mahdi Alzhrani, et al.
Published: (2020)

Synthesis and Biological Evaluation of 1,2,3-Triazole Tethered Thymol-1,3,4-Oxadiazole Derivatives as Anticancer and Antimicrobial Agents
by: Abdulraheem S. A. Almalki, et al.
Published: (2021)

Synthesis, characterization and biological evaluation of novel 2,5 substituted-1,3,4 oxadiazole derivatives
by: Selvaraj Kavitha, et al.
Published: (2017)

Synthesis and characterization of 5-aryl-1,3,4-oxadiazole-2(3h)thione derivatives
by: Shailesh Pathak, et al.
Published: (2020)

Synthesis, characterization, antimicrobial, and pharmacological evaluation of some 2, 5-disubstituted sulfonyl amino 1,3,4-oxadiazole and 2-amino-disubstituted 1,3,4-thiadiazole derivatives
by: Dilipkumar Pal, et al.
Published: (2014)

Exploring Probenecid Derived 1,3,4-Oxadiazole-Phthalimide Hybrid as α-Amylase Inhibitor: Synthesis, Structural Investigation, and Molecular Modeling
by: Bilal Ahmad Khan, et al.
Published: (2023)

Synthesis of Some Substituted 1,3,4-Oxadiazoles, Thiadiazoles and 1,2,4-Triazoles from Acid Chlorides
by: E. Q. Mahmood, et al.
Published: (2013)

Synthesis and characterization Studies of Mixed Ligand (1,3,4-oxadiazole derivative and ethylenediamine or acetylacetone)complexes with Ni(II)
by: Rezhna Faraj, et al.
Published: (2013)

Synthesis, Antibacterial study and ADME Evaluation of Novel Isonicotinoyl Hydrazide Derivative Containing 1,3,4-Oxadiazole Moiety
by: Mazen Mohammed Jwaid, et al.
Published: (2022)

Synthesis Of 2-Benzamidomethyl-5-Substituted Amino-1,3,4-Thiadiazoles-2,5-Disubstituted 1,3,4-Oxadiazole and 4,5-Disubstituted 1,2,4-Triazole-3-Thiol
by: K. M. Daoud, et al.
Published: (2012)

1,3,4-Oxadiazole-naphthalene hybrids as potential VEGFR-2 inhibitors: design, synthesis, antiproliferative activity, apoptotic effect, and in silico studies
by: Mohamed Hagras, et al.
Published: (2022)

In silico and antithrombotic studies of 1,3,4-oxadiazoles derived from benzimidazole
by: B. Vishwanathan, et al.
Published: (2015)

Biologically oriented synthesis of medicines (BIODS) based on heterylpoxid 2,5-disubstituted 1,3,4-oxadiazoles (Part 2)
by: Yu. V. Karpenko, et al.
Published: (2021)

Biologically oriented synthesis of medicines (BIODS) based on heterylpoxid 2,5- disubstituted 1,3,4-oxadiazoles (Part 1)
by: Yu. V. Karpenko, et al.
Published: (2020)

Synthesis, Computational Studies, Antioxidant and Anti-Inflammatory Bio-Evaluation of 2,5-Disubstituted-1,3,4-Oxadiazole Derivatives
by: Sibghat Mansoor Rana, et al.
Published: (2023)

Synthesis and Study of Some 4-Chlorophenoxy Methyl Substituted amido1,3,4-Oxadiazoles, 1,3,4-Thiadiazoles and 1,2,4-Triazoles from 4-Chloro phenoxy acetic acid
by: Mudhar A. Othman, et al.
Published: (2013)

The study of antiexudative action of S-alkylated 1,3,4-oxadiazole-3-thionе derivatives
by: Yu. L. Shepeta, et al.
Published: (2019)

Synthesis of some substituted 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles from 2-(2,3-dimethylphenyl amino) benzoic acid
by: Khalid Daoud, et al.
Published: (2009)

Synthesis and Biological evalution of some substituted 2-dibenzyl amino 1,3,4-oxadiazoles , thiadiazoles and 1,2,4-triazoles
by: Khalid Daoud, et al.
Published: (2013)

Synthesis of Some 1,4-Bis (Substituted 1,3,4-Oxadiazoles and 1,2,4-Triazoles) Benzene From Terephthalic Acid
by: K. Daoud, et al.
Published: (1999)

Synthesis, telomerase inhibitory and anticancer activity of new 2-phenyl-4H-chromone derivatives containing 1,3,4-oxadiazole moiety
by: Xu Han, et al.
Published: (2021)

Synthesis, anticancer evaluation and molecular docking studies of new benzimidazole- 1,3,4-oxadiazole derivatives as human topoisomerase types I poison
by: Ulviye Acar Çevik, et al.
Published: (2020)