Combinatory antitumor therapy by cascade targeting of a single drug

• Main Authors: Aiyun Liu (Author), Huaisong Wang (Author), Xiaoshuang Hou (Author), Yu Ma (Author), Gongjun Yang (Author), Yanglong Hou (Author), Ya Ding (Author)
• Format: Book
• Published: Elsevier, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Combination therapy has shown its promise in the clinic for enhancing the efficacy of tumor treatment. However, the dose control of multiple drugs and their non-overlapping toxicity from different drugs are still great challenge. In this work, a single model drug, paclitaxel (PTX), is used to realiz...