Use of Antioxidants for the Neuro-Therapeutic Management of COVID-19

Coronavirus Disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is an emergent infectious disease that has caused millions of deaths throughout the world. COVID-19 infection's main symptoms are fever, cough, fatigue, and neurological manifestations s...

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Main Authors: Noemí Cárdenas-Rodríguez (Author), Cindy Bandala (Author), América Vanoye-Carlo (Author), Iván Ignacio-Mejía (Author), Saúl Gómez-Manzo (Author), Estefani Yaquelin Hernández-Cruz (Author), José Pedraza-Chaverri (Author), Liliana Carmona-Aparicio (Author), Beatriz Hernández-Ochoa (Author)
Format: Book
Published: MDPI AG, 2021-06-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Noemí Cárdenas-Rodríguez  |e author 
700 1 0 |a Cindy Bandala  |e author 
700 1 0 |a América Vanoye-Carlo  |e author 
700 1 0 |a Iván Ignacio-Mejía  |e author 
700 1 0 |a Saúl Gómez-Manzo  |e author 
700 1 0 |a Estefani Yaquelin Hernández-Cruz  |e author 
700 1 0 |a José Pedraza-Chaverri  |e author 
700 1 0 |a Liliana Carmona-Aparicio  |e author 
700 1 0 |a Beatriz Hernández-Ochoa  |e author 
245 0 0 |a Use of Antioxidants for the Neuro-Therapeutic Management of COVID-19 
260 |b MDPI AG,   |c 2021-06-01T00:00:00Z. 
500 |a 10.3390/antiox10060971 
500 |a 2076-3921 
520 |a Coronavirus Disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is an emergent infectious disease that has caused millions of deaths throughout the world. COVID-19 infection's main symptoms are fever, cough, fatigue, and neurological manifestations such as headache, myalgias, anosmia, ageusia, impaired consciousness, seizures, and even neuromuscular junctions' disorders. In addition, it is known that this disease causes a series of systemic complications such as adverse respiratory distress syndrome, cardiac injury, acute kidney injury, and liver dysfunction. Due to the neurological symptoms associated with COVID-19, damage in the central nervous system has been suggested as well as the neuroinvasive potential of SARS-CoV-2. It is known that CoV infections are associated with an inflammation process related to the imbalance of the antioxidant system; cellular changes caused by oxidative stress contribute to brain tissue damage. Although anti-COVID-19 vaccines are under development, there is no specific treatment for COVID-19 and its clinical manifestations and complications; only supportive treatments with immunomodulators, anti-vascular endothelial growth factors, modulating drugs, statins, or nutritional supplements have been used. In the present work, we analyzed the potential of antioxidants as adjuvants for the treatment of COVID-19 and specifically their possible role in preventing or decreasing the neurological manifestations and neurological complications present in the disease. 
546 |a EN 
690 |a COVID-19 
690 |a SARS-CoV-2 
690 |a antioxidants 
690 |a oxidative stress 
690 |a neurological damage 
690 |a neuro-therapeutic management 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Antioxidants, Vol 10, Iss 6, p 971 (2021) 
787 0 |n https://www.mdpi.com/2076-3921/10/6/971 
787 0 |n https://doaj.org/toc/2076-3921 
856 4 1 |u https://doaj.org/article/079b0925ddcb4b5ea9d156ce1acadce4  |z Connect to this object online.