Modeling Composite Assessment Data Using Item Response Theory

Composite assessments aim to combine different aspects of a disease in a single score and are utilized in a variety of therapeutic areas. The data arising from these evaluations are inherently discrete with distinct statistical properties. This tutorial presents the framework of the item response th...

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Bibliographic Details
Main Author: Sebastian Ueckert (Author)
Format: Book
Published: Wiley, 2018-04-01T00:00:00Z.
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Summary:Composite assessments aim to combine different aspects of a disease in a single score and are utilized in a variety of therapeutic areas. The data arising from these evaluations are inherently discrete with distinct statistical properties. This tutorial presents the framework of the item response theory (IRT) for the analysis of this data type in a pharmacometric context. The article considers both conceptual (terms and assumptions) and practical questions (modeling software, data requirements, and model building).
Item Description:2163-8306
10.1002/psp4.12280